Methamphetamine (meth) increases monoamine oxidase (MAO)-dependent mitochondrial stress in axons of substantia nigra pars compacta (SNc), and ventral tegmental area (VTA) dopamine neurons.Chronic administration of meth results in SNc degeneration and MAO inhibition is neuroprotective, whereas, the VTA is resistant to degeneration.This differential
Abstract Inappropriate prescribing (IP) in older patients is highly prevalent and is associated with an increased risk of adverse drug events (ADEs), morbidity, mortality and healthcare utilisation.Consequently, IP is a major safety concern and with changing population demographics, it is likely DC Brushless Fan to become even more prevalent in the
Epilepsy remains a significant non-communicable disease with global health relevance.The World Health Organization (WHO) estimates that between 4 and 10 per 1000 people worldwide suffer from active epilepsy, with the African population having the highest Leather Flask associated morbidity and mortality.This review highlights the prevalence of epile
The study of social-ecological systems (SES) is an inherently interdisciplinary endeavor that necessitates collaboration among multiple researchers and stakeholders.These collaborations often result in novel insights into the dynamics and feedbacks that occur within these systems.Achieving these insights requires methods and tools that integrate di
Introduction: The treatment of large renal stones in children can be challenging often requiring combination therapy and multiple procedures.The purpose of this video is to describe our technique LED Signs of robotic nephrolithotomy and pyelolithotomy for complex renal stone disease in children, and to demonstrate the utility of the robotic ultraso